E.P.A. Grant to University of Chicago for Research on Food Allergy Triggers

WASHINGTON - The E.P.A. has awarded a $433,100 grant to the University of Chicago to investigate how allergic reactions to food are initiated. The research is expected to lead to improved methods to assess whether pesticides produced in genetically engineered plants can trigger food allergies. The study is funded through EPA's Science to Achieve Results plan (STAR).

"There is a shortage of information on how food allergies develop, what causes the allergic reaction, and how to prevent them," said Lek Kadeli, acting assistant administrator for the Office of Research and Development. "This study will bring us closer to identifying key immune factors that lead to food allergies, which affect approximately three million children in the United States."

The University of Chicago, in conjunction with Northwestern University, will work to determine why specific antibodies start reacting to foods and allergens when they are eaten. Understanding this process will help determine how food can trigger an allergic response and could help predict the potential for people to develop allergies to new genetically engineered foods. With better understanding of how foods trigger allergic responses, scientists will be equipped to develop new tests for adverse effects from these foods and interpret data from toxicity tests required by regulation.

Each year, food allergies impact in excess of eleven million Americans each year, instigate in excess of 30,000 emergency room visits, and in rare cases can lead to death. The number of allergy-related incidences in the U.S. doubled between 1997 and 2002.

E.P.A. regulates the use of all pesticides in the United States, establishes acceptable levels for pesticide residues in food, and evaluates human health and ecological risks under authority of the Federal Insecticide, Fungicide, and Rodenticide Act and the Federal Food, Drug, and Cosmetic Act.

More information on the study: http://www.epa.gov/ncer/uchicago/foodallergy/

More information on EPA's STAR program: http://www.epa.gov/ncer/grants/

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